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Current Trainees

Adelaja, Adewunmi – Predoc Trainee

Mentor: Alexander Hoffmann
Research Project: Regulation of NFkB dynamics in healthy and disease-associated macrophages

Allan, Christopher – Postdoctoral Trainee

Mentor: Stephen G. Young
Research Project: The function of GPIHBP1 domains in intravascular lipolysis
Publications:

Allan CM, Award AM, Johnson JS, Shirasaki DI, Wang C, Blaby-Haas CE, Merchant SS, Loo JA, Clarke CF. 2015. Identification of Coq11, a new coenzyme Q biosynthetic protein in the coQ-synthome in Saccharomyces cerevisiae. J Biol. Chem. 290:7517-7534.

Allan CM, Hill S, Morvaridi S, Saiki R, Johnson JS, Liau WS, Hirano K. Kawashima T, Ji Z, Loo JA, Shepherd JN, Clarke CF. 2012. A conserved START domain coenzyme Q-binding polypeptide is required for efficient Q biosynthesis, respiratory electron transport and antioxidant function in Saccharomycws cerevisiae. Biochim Biophys Acta. 1831:776-791.

Archer, Brian – Pre-doc Trainee

Mentor: Louis Bouchard
Research Project: Controlled vascularization in a three-dimensional liver organoid.

Engel, James – Predoctoral Trainee

Mentor: Reza Ardehali

Research Project: Reprogramming of cardiac fibroblast subpopulations to endothelial cells using modified RNA

Publications:

Skelton RJ, Brady B, Sahoo D, Engel JL, Abilez O, Hojjat A, Khoja S, Zhao P, Kwon M, Elliott DA, Ardehali R. CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from human embryonic stem cells. Stem Cell Reports. 2016 Jan 12;6(1):95-108.

Skelton RJ, Almeida S, Rapacchi S, Han F, Khoja S, Engel JL, Zhao P, Peng H, Stanley E, Elefanty A, Kwon M, Elliott DA, Ardehali R. Magnetic resonance imaging of iron oxide labeled human embryonic stem cell derived cardiac progenitors. Stem Cells Transl Med. 2016 Jan; 5(1):67-74.

Girard, Juliet – Post-doc Trainee

Mentor: Utpal Banerjee

Research Project: Investigating Cell Cycle Regulation in Blood Cell Progenitors

Publications:

Girard JR, Tenthorey JL, and Morgan DO. 2015. An E2 accessory domain increases affinity for the anaphase-promoting complex and ensures E2 competition. J. Biol. Chemistry 290:24614-25.

Lu D, Girard JR, Mizrak A, and Morgan DO. 2015. Quantitative framework for ordered degradation of APC/C substrates. BMC Biology 13:96.

Hu, Xuchen – PRE-DOC TRAINEE

Mentor: Stephen G. Young

Research Project: Mechanisms for Intravascular Lipolysis

Publications:

Quintero-Rivera F, Xi QJ, Keepler-Noreuil KM, et al. MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus. Hum Mol Genet. 2015;24(8):2375-89.

Lee, Josh – Pre-doc Trainee

Mentor: Yibin Wang

Research Project: Investigating the maturation of stem cell derived cardiomyocytes by Rbfox proteins.

Publications:

Jing Z, Gangalum RK, Lee JZ. 2013. Cell-type-dependent access of HSF1 and HSF4 to a B-crystallin promoter during heat shock. Cell Stress and Chaperones. 18:377-87.

Gangalum RK, Jing Z, Bhat AM, Lee J, Nagaoka Y, Deng SX, Jiang M, Bhat SP. 2014. Expression of the HSF4 DNA binding domain-EGFP hybrid gene recreates early childhood lamellar cataract in transgenic mice. Invest Ophthalmol Vis Sci. 55:7227-40.

Park, Shuin – Pre-doc Trainee

Mentor: Reza Ardehali

Research Project: Determining the role of cardiac pericytes in angiogenesis and fibrosis.

Sandhu, Jaspreet – Pre-doc Trainee

Mentor: Peter Tontonoz

Research Project: Regulation of system cholesterol flux by LXR and IDOL

Publications:

Nguyen HT, Sandhu J, Langousis G, Hill KL. 2013. CMF22 is a broadly conserved axonemal protein and is required for propulsive motility in Trypanosoma brucei. Eukaryot Cell. 12:1202-13. PMCID: PMC3811564

Ziyad, Safiyyah – Postdoctoral Trainee

Mentor: Luisa Iruela-Arispe
Research Project: Genetic Basis of Vascular Malformations

Publications:

Domigan CK, Warren CM Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, Iruela-Arispe ML. 2015. Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. J Cell Sci. 128:2236-48. PMCID 44887014

Ziyad S, Iruela-Arispe ML. 2011. Molecular mechanisms of tumor angiogenesis. Genes Cancer. 2:1085-96. PMCID: PMC3411131